Using various pain models, studies can be done with such measured responses as
- Number of complete crosses
- Time to exit the light chamber (latency)
- Time to cross the probes, etc.
- Significant stimulus response relationships have been observed between probe height and these measured responses.
The MCS – Harte, Morrow Method provides an operant method of pain testing with rodents that complements reflexive methods by addressing cognitive and motivational processing. Rodents are placed on one side of a height-adjustable array of nociceptive probes and given the opportunity to cross the array to escape from an aversive lighted area to a preferred dark area. The array consists of blunt tapered probes that are painful but not sharp enough to cause any tissue damage when walked on by the rodent.
*Animal training is fast and simple